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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:apremilast
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Accession:CHEBI:78540 term browser browse the term
Definition:A member of the class of isoindoles that is isoindole-1,3-dione substituted at position 4 by an acetamido group and at position 1 by a 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl group. Used for treatment of psoriatic arthritis.
Synonyms:exact_synonym: N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide
 related_synonym: CC-10004;   CC10004;   Formula=C22H24N2O7S;   InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1;   InChIKey=IMOZEMNVLZVGJZ-QGZVFWFLSA-N;   OTEZLA;   SMILES=CCOc1cc(ccc1OC)[C@@H](CS(C)(=O)=O)N1C(=O)c2cccc(NC(C)=O)c2C1=O;   apremilastum
 xref: CAS:608141-41-9;   Drug_Central:4829;   KEGG:D08860
 xref_mesh: MESH:C505730
 xref: PMID:22910104;   PMID:22984171;   PMID:23030767;   PMID:23569359;   PMID:23588944;   PMID:23663752;   PMID:23986162;   PMID:24072562;   PMID:24592316;   PMID:24595547;   PMID:24702658;   PMID:24797159;   PMID:24846499;   PMID:24852768;   PMID:24869713;   PMID:24882690;   PMID:24962564;   PMID:24979544;   PMID:24997741;   PMID:24998661;   PMID:25027606;   PMID:25050054;   PMID:25054629;   Reaxys:12446985;   Wikipedia:Apremilast

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Path 1
Term Annotations click to browse term
  CHEBI ontology 2
    role 2
      application 2
        anti-inflammatory agent 0
          anti-inflammatory drug 0
            non-steroidal anti-inflammatory drug 0
              apremilast 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 2
    subatomic particle 2
      composite particle 2
        hadron 2
          baryon 2
            nucleon 2
              atomic nucleus 2
                atom 2
                  main group element atom 2
                    p-block element atom 2
                      carbon group element atom 2
                        carbon atom 2
                          organic molecular entity 2
                            heteroorganic entity 2
                              organochalcogen compound 1
                                organooxygen compound 0
                                  carbon oxoacid 0
                                    carboxylic acid 0
                                      carboacyl group 0
                                        univalent carboacyl group 0
                                          carbamoyl group 0
                                            carboxamide 0
                                              acetamides 0
                                                N-acetylarylamine 0
                                                  apremilast 0
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